25 Sep
Enrollment and Demographics Two-hundred-sixty-four women were contacted through the telephone survey. Ten women declined the interview, and 13 women began the interview but did not finish. Thirty percent of the women were not able to participate fiirther in the study because they had not heard of SCD. A total of 162 African-American women met all [...]
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25 Sep
The results of our study indicate that 30% of the African-American women of childbearing age in the study are unaware of SCD. Of those who completed the survey, most women understood that SCD was a hereditary blood disorder but did not understand the inheritance pattern and believed that SCD skipped generations. The results of this [...]
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25 Sep
METHODS Data Collection The Institutional Review Board at Washington University School of Medicine approved this study. An independent marketing research corporation, Fleming Communications, conducted a cross-sectional telephone survey of African-American women in the St. Louis metropolitan area from July 31, 2001 to August 17, 2001. Individuals were identified through random-digit dialing of a population of [...]
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25 Sep
INTRODUCTION Sickle cell disease (SCD) is the most common genetically inherited disease affecting African Americans. Approximately one in 12 African Americans will have sickle cell trait, and approximately one in 400 African-American newborns will be diagnosed with SCD annually. Prior to the 1970s, few programs were dedicated to providing the public with information on SCD. [...]
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22 Sep
Up to 8.4% of pregnant women may be affected by asthma, which, if uncontrolled, can lead to adverse perinatal outcomes. Although National Asthma Education and Prevention Program Guidelines recommend the use of ICSs for the treatment of all severities of persistent asthma during pregnancy, few studies have assessed the safety of ICSs in pregnant women. [...]
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22 Sep
Systemic corticosteroid use is a documented risk factor for the development of cataracts, but pediatric and adult study data argue against a large effect of ICS use on cataract development. In children, analysis of data from the CAMP study demonstrated the presence of one posterior subcapsular cataract among 311 children who received inhaled budesonide medication, [...]
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22 Sep
The hypothalamic pituitary adrenal (HPA) axis is very sensitive to the systemic activity of corticosteroids and is thus a useful indicator of systemic activity of ICSs; however, the clinical relevance of minor changes in the HPA axis is unclear. A decrease in endogenous Cortisol production is expected, with systemic exposure to exogenous corticosteroids due to [...]
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