Archive for June, 2010

30 Jun

USP Prescription for Safety

This simple recipe for opium tincture from the 19th century was considered quite an achievement in its time. Published by the  United States Pharmacopeia (USP), early monographs like this one provided practitioners with the assurance that their patients were getting carefully prepared medicines and were using them correctly.

29 Jun

Prophylactic Ethics

We are unaccustomed to seeing the juxtaposition of the words that are in the title of this editorial. Indeed, I first heard this combination of words used in March 2002 at a special conference sponsored by our Office of Health Policy and Clinical Outcomes at Thomas Jefferson University in Philadelphia. The conference, entitled “Preparing Medical [...]

28 Jun

Antimicrobial Agents and Chemotherapy: New Prophylactic Antifungal Agent for Patients Undergoing Hematopoietic Stem Cell Transplantation

Speaker: Jo-Anne van Burik, MD, Assistant Professor of Medicine, Division of Infectious Diseases, Department of Medicine, University of Minnesota, Minneapolis, Minnesota. Micafungin (Fujisawa Healthcare, Inc.), a member of a new class of antifungal agents known as the echinocandins, has demonstrated a greater overall success rate than fluconazole (Generic Diflucon, Pfizer) as antifungal prophylactic therapy and [...]

27 Jun

Antimicrobial Agents and Chemotherapy: Nucleotide Reverse Transcriptase Inhibitors in Treatment-Naive, HIV-Positive Patients

Speaker: Joel Gallant, MD, Associate Professor of Medicine, Department of Infectious Disease, Johns Hopkins University School of Medicine, Baltimore. A tenofovir disoproxil fumarate (TDF) (Viread®, Gilead)-based regimen has proved to be as effective in maintaining undetectable levels of HIV RNA as a medication stavudine (d4T) (Zerit canadian, Bristol Myers Squibb)-based regimen in treatment-naive, HIV-infected patients, [...]

26 Jun

Antimicrobial Agents and Chemotherapy: Boosted Protease Inhibitor Therapy in Treatment-Experienced, HIV-Infected Patients

Speaker: Jan Gerstoft, MD, Senior Consultant, Rigs Hospi-talet, Copenhagen, Denmark. A 48-week trial on the efficacy and safety data is the first head-to-head study of ritonavir (Novir medication, Abbott)-boosted protease inhibitor (PI) therapy in treatment-experienced patients with human immunodeficiency virus (HIV) infection. Results indicated that saquinavir (Fortovase®, Roche)/ritonavir reduced HIV levels to less than 50 [...]

25 Jun

Antimicrobial Agents and Chemotherapy

Once-Daily Short-Duration Antimicrobial Therapy for Community-Acquired Pneumonia Speaker: John Pullman, MD, Infectious Diseases Specialist, Internal Medicine, Mercury Medical Center, Butte, Montana. Telithromycin (Ketek™, Aventis), administered once daily for five to ten days to patients with CAP, has been found to be as effective and safe as standard twice-daily, 10-day treatment with clarithromycin (Biaxin tablet, Abbott), [...]

24 Jun

The Struggle to Heal an Angry Patient

How are you doing?” I cautiously asked. “Pretty bad,” he sarcastically answered. “How would you be doing if your body was full of cancer and your doctors told you there was nothing they could do?” It was a typical answer from him and I immediately regretted asking the question. “Is that really what your oncologist [...]

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