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Melanoacanthoma’s histopathologic appearance is very helpful in diagnosis, and is characterized by a hyperplastic epidermis, large dendritic melanocytes and nonpigmented keratinocytes. Numerous large dendritic melanin-laden melanocytes were spread throughout the tumor at all levels of spinous layer. This case also showed these histopathologic features, and positive staining with S-100 protein, HMB-45 and Fontana-Masson. Differential diagnoses [...]

Seborrheic keratosis is a benign cutaneous tumor, which is more common in those aged over 40 years. It has been known to originate from the proliferation of epidermal keratinocytes. It is very common in white races, and both sexes are equally affected. The patient with seborrheic keratosis is often uncon­cerned by his/her disease believing it [...]

A 68-year-old man presented with an asymp­tomatic pigmented plaque on his right shin of 5 years’ duration. The size of the pigmented lesion had slowly increased during the last year. Physical examination revealed a single, oval shaped, verru­cous, dark-brown to black pigmented plaque measur­ing 2 x 2 cm on the right shin (Fig, 1), The [...]

INTRODUCTION Melanoacanthoma is a term first introduced by Mishima and Pinkus in I960, This is a rare benign tumor of both melanocytes and keratinocytes. Clinical manifestation is usually a slow-growing, painless, pigmented plaque with verrucous surface with a diameter ranging from a few millimeters to 10 cm. It is characterized histologically by nonpig­mented keratinocytes and [...]

Milia en plaque, a rare subtype of primary milia, is characterized by asymptomatic unilateral or bilateral erythematous, edematous or indurated plaques within which are multiple, whitish-to-yello­wish, 1 to 2 mm sized papules. In most of the previous reports, the lesions were located in the periauricular area. A few cases have been reported involving other sites, [...]

A 11 year-old girl presented with multiple, asymptomatic, 1 to 2 mm sized, white and firm papules based on a linear erythematous plaque from the right forehead to the nasal bridge (Fig. 1). The plaque was slightly pinkish in color with a well-circumscribed border. The plaque arose spontan­eously on the right side of the forehead [...]

INTRODUCTION Milia en plaque (МЕР) is a rare clinical variant of milia. The group of milia forming a plaque was first described by Baizer and Fouquet in the retroauricular area in 1903 . The term ilia en plaque vas given to this atypical clinical form by Hubler et al in 1978. It arises spontaneously in [...]