31 Mar
Lung cancer is the most common cause of cancer death in North America. The overall five-year survival of patients with lung cancer ranges from 10 to 13 percent. In patients with early lung cancer (TIS NO MO and T1 NO MO), the five-year survival is over 90 percent after surgical resection. Fluorescence bronchoscopy following administration [...]
Posted in cancer by: Steve
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30 Mar
Particular mention should be made of the study of Weber et al on a group of asthmatic subjects. They found that 12 weeks of treatment with inhaled terbu- taline resulted in a decrease in the peak response of FEV1 to terbutaline. These results seem to differ from ours though the designs of the two studies [...]
Posted in Diseases by: Steve
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29 Mar
The results of this study demonstrated that in patients with severe COPD, therapy with inhaled salbutamol in the usual doses appeared to decrease the duration of the bronchodilation produced by the same agent, while the peak response remained relatively stable. Stopping sustained-release theophylline for 12 h before study in the laboratory may not be long [...]
Posted in Diseases by: Steve
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28 Mar
Of 12 patients selected, one had an exacerbation of COPD during treatment with ipratropium bromide and was excluded. Baseline clinical data from the 11 patients who successfully completed the study are shown in Table 1. The average patient was elderly, had a significant smoking history, severe airway obstruction and hyperinflation.
Posted in Diseases by: Steve
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27 Mar
Twelve patients were entered into the study, selected from a large pool of patients attending our pulmonary clinic. Selection criteria included a clinical diagnosis of COPD, a history of cigarette smoking, an FEV,-value of less than 60 percent of predicted normal and less than 2 L, a TLC value of more than 80 percent of [...]
Posted in Diseases by: Steve
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26 Mar
The issue of tolerance or tachyphylaxis to adrenergic agents is not new. When the rise and fall in asthma deaths in the 1960s was seen to parallel sales of adrenergic inhalers, it was suggested that patients taking large doses of sympathomimetics might become tolerant to drug effect and even to endogenous catecholamines during an asthma [...]
Posted in Diseases by: Steve
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25 Mar
Ten previous cases of iatrogenic aortocoronary saphenous vein bypass graft to coronary vein fistulas have been described. Seven of these ten coronary fistulas have involved the great cardiac vein in its proximal portion adjacent to the LAD coronary artery. The left marginal coronary vein has been involved twice and the posterior intraventricular coronary vein has [...]
Posted in Main by: Steve
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