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Clinical findings indicate that primary hypercalciuria predispos­es affected subjects to nephrolithiasis and nephrocalcinosis, even though its specific pathogenetic role has not been eluci­dated in both disorders. The effect of hypercalciuria is likely to depend on unusually high calcium concentrations in urine or tubular fluid of patients. When calcium concentrations exceed the threshold for precipitation, calcium [...]

An alteration of calcium metabolism has been hypothesized in patients with arterial hypertension and could be revealed by hy- percalciuria. Many strains of hypertensive rats are hyper- calciuric, suggesting that hypercalciuria and hypertension may share a common genetic substrate. High calcium excretion can be found also in hypertensive patients and the prevalence of hypercalciuria among [...]

Renal deposition of calcium-phosphate or calcium-oxalate re­sults in nephrocalcinosis. This disorder is more frequently found in children and preterm newborns and deposits are more frequently composed by apatite and begins within medulla. In rare patients with primary hyperoxaluria (type 1 or 2) deposits are cortical and composed by calcium-oxalate. Nephrocalcinosis may occur in the course [...]

Kidney stone disease may be considered as the main compli­cation of hypercalciuria. Despite the amount of research, the first evidence that hypercalciuric subjects are predisposed to kidney stones was recently provided in a work, displaying that the risk to produce stones increased with calcium excretion in general population. Previous studies had limited their ob­servation to [...]

In most of patients, primary hypercalciuria results from an in­crease of intestinal calcium absorption (absorptive hypercalci­uria). In less than 5% of patients, primary hypercalciuria may be caused by a primary defect in tubular calcium reab- sorption (renal hypercalciuria). These different forms of hypercalciuria are clinically distinguished with the measure­ments of fasting calcium excretion and plasma [...]

Introduction Primary hypercalciuria is a defect of calcium metabolism, char­acterized by increased 24 hour urinary calcium excretion which is not justified by any apparent metabolic alteration. Its prevalence is 5-10% in the general population, but is signifi­cantly higher in patients with calcium kidney stones, nephrocalcinosis, arterial hypertension and osteoporosis. Online Canadian pharmacy mycanadianhealthcare.com Primary hypercalciuria [...]

Recurrence of hemoptysis following an initially successful BAE is more common. The most important causes are incomplete embolization, progression of the native disease, and recanalization of the embolized vessels. Probably all three factors operate in each patient, to a varying degree. The first two are clearly more important. Incomplete embolization is often due to inadequate [...]