Generic versions of Prozac (fluoxetine) have been available to patients for approximately 18 months, and a court decision is expected this month on whether generic Paxil (paroxetine hydrochloride) may be marketed. Yet in the face of this, several SSRI brands have increased HMO drug formulary access.
As I sat listening to her, my mind was searching for the right words to say. She had come seeking my advice, yet I knew it was the last thing she wanted to hear.
She was a lovely 24-year-old woman. Two years earlier, she had graduated from college. And she had to grow up in a [...]
There are several contraindications for the use of FluMist™:
1. Under no circumstances should the vaccine be administered parenterally.
2. Individuals with a history of hyper-sensitivity—especially anaphylactic reactions—to any component of Flu-Mist™, including eggs or egg products, should not receive this vaccine.
3. FluMist™ should not be given to children (ages five to 17) who are receiving aspirin [...]
A multicenter, randomized, double-blind, placebo-controlled trial was conducted to evaluate the efficacy of FluMist™ in reducing influenza illness during a seven-week, site-specific peak outbreak period. The trial included 3,920 healthy adults aged 18 to 49 throughout the U.S. who were randomly selected to receive the vaccine or a placebo (in a ratio of 2:1).
FluMist™ is an intranasal, live, attenuated, trivalent, cold-adapted, and temperature-sensitive vaccine. The immune mechanisms that confer protection against influenza following administration of this vaccine are not fully understood, and naturally acquired immunity to wild-type influenza has not been completely clarified. It is possible that serum antibodies, mucosal antibodies, and influenza-specific T cells might be involved [...]
INTRODUCTION
Influenza, commonly referred to as the flu, is an acute, contagious, and self-limited disease that directly affects the respiratory tract. Approximately 10% to 20% of Americans experience illness because of influenza each year, resulting in a significant loss in work and productivity that directly and indirectly translates into financial costs. Each year, from $3 billion [...]
The potential for drug interactions with ximelagatran has been described in various in vitro and in vivo studies. In general, ximelagatran demonstrated a low potential for drug interactions based on several factors:
The mechanism of action of ximela-gatran was not affected by vitamin K-dependent clotting factors.
The plasma protein binding of mela-gatran was relatively low.
The elimination route [...]
© 2008 HIV/AIDS News & Information