Archive for the 'Health' Category

17 Jan

Test and treat strategies for Helicobacter part 2

UBT is considered by many to be the gold standard non- invasive test for the detection of active H pylori infection. After a 4 h fast, the patient ingests carbon- or carbon- labelled urea, which is metabolized to carbon dioxide by the H pylori-associated urease. The labelled carbon dioxide is then absorbed, and the increased […]

16 Jan

Test and treat strategies for Helicobacter

Test and treat strategies for Helicobacter pylori in uninvestigated dyspepsia: A Canadian economic analysis. By convention, the term ‘dyspepsia’ is used to describe a symptom complex of chronic or recurrent pain or dis­comfort in the upper abdomen that is attributable to the up­per gastrointestinal tract. Although variably defined in the literature, dyspepsia imposes a substantial […]

02 Jan

Vitamin D and muscle function

One meta-analysis addressed the effect of vitamin D on the risk of falling in older persons. Based on 5 RCTs (n = 1237), vitamin D reduced the risk of falling by 22% (pooled cor­rected OR = 0.78; 95% CI [0.64, 0.92]) compared to calcium or placebo (10, 16, 20-22). Subgroup analyses suggested that the reduction […]

01 Jan

Vitamin D and muscle function

Maintenance of musculoskeletal function and fall prevention are important public health targets in a rapidly aging population. Sarkopenia is prevalent in older persons and resulting in falls among 30% percent of those 65 years or older, and 40­50% of those 80 years or older. Several beneficial effect of vitamin D have been described, the most […]

17 Dec

Genetic polymorphisms of vitamin D receptor and calcium sensing receptor gene: Discussion

Patients on long term hemodialysis caused by chronic renal failure commonly have accompanying renal bone disease, one of the major factors underlying this disease being secondary hyperparathyroidism. Parathyroid hyperplasia and high levels of immunoreactive PTH are present in the early stage of sec­ondary hyperparathyroidism. Clonal analysis has shown that in renal hyperparathyroidism the parathyroid glands […]

10 Dec

Genetic polymorphisms of vitamin D receptor and calcium sensing receptor gene: Results

The frequency distribution of VDR and CaSR genotypes were in Hardy-Weinberg equilibrium. The distribution of Apa I a nd Taq I genotypes was very similar to what previously reported in Caucasian populations of European ancestry, while significant­ly differed from what observed in populations of Asiatic ances­try. The distribution of CaSR genotypes did not vary from […]

06 Dec

Genetic polymorphisms of vitamin D receptor and calcium sensing receptor gene: Materials and methods

Subjects The study population comprised 100 patients affected with ure­mic secondary HPT and 200 age and sex matched controls. Patients had been recruited as part of a multicentric Italian study, including the Nephrology and Dyalisis Units of Bari, Cinisello Balsamo, Desio, Florence, Milan and Reggio Emilia. The inclusion criteria for the study were the following: […]

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